BDBM50428083 CHEMBL2323568::US9303017, (S)-16, YL-1-169

SMILES CCCCC#Cc1cnc(C)c(OC[C@@H]2CCCN2)c1

InChI Key InChIKey=CZWUYUYQOZHEAK-INIZCTEOSA-N

Data  9 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50428083   

TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Rattus norvegicus (Rat))
Georgetown University

US Patent
LigandPNGBDBM50428083(CHEMBL2323568 | US9303017, (S)-16, YL-1-169)
Affinity DataKi:  9.40E+4nM ΔG°:  -5.10kcal/molepH: 7.4 T: 2°CAssay Description:Briefly, cultured cells at >80% confluence were removed from their flasks (80 cm^2) with a disposable cell scraper and placed in 10 mL of 50 mM Tris....More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Rattus norvegicus (Rat))
Georgetown University

US Patent
LigandPNGBDBM50428083(CHEMBL2323568 | US9303017, (S)-16, YL-1-169)
Affinity DataIC50:  6.40E+3nMAssay Description:IC50(10′): The functional properties of the ligands were determined by 86Rb+ efflux assays in cells expressing α3β4 and α4β...More data for this Ligand-Target Pair
In DepthDetails US Patent